Dr. Franchi talks about treatment of certain joints in which implants and joint replacements are not successful; specifically, ankles, wrists, elbows and the great toe of your foot. In these cases, the implants do not work very well; therefore, you are left with a choice of the fusion of the joint. The downside of this, is that you will have a stiff joint after. A fusion causes the transference of the stress, that was normally taken up by that joint, to the joints above and below the fusion. As a result, a patient will eventually develop arthritis in those joints. Additionally, a patient will have limited range of motion. Prolotherapy can successfully treat these conditions, successfully, and a patient can avoid this.